AdipoGen Life Sciences

RANK (human):Fc (human) (rec.)

CHF 240.00
In stock
AG-40B-0018-C05050 µgCHF 240.00
AG-40B-0018-30503 x 50 µgCHF 480.00
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Product Details
Synonyms TRANCE-R; TNFRSF11A; ODFR; Osteoclast Differentiation Factor Receptor; CD265
Product Type Protein
Properties
Source/Host HEK 293 cells
Sequence

Human RANK (aa 29-213) is fused at the C-terminus to the Fc portion of human IgG1.

Crossreactivity Human
Mouse
Specificity

Binds to human and mouse RANKL.

Biological Activity

Inhibits human rhsRANKL biological functions.

MW ~55kDa (SDS-PAGE)
Purity ≥95% (SDS-PAGE)
Endotoxin Content <0.01EU/μg purified protein (LAL test; Lonza).
Concentration 1mg/ml after reconstitution.
Reconstitution Reconstitute with 50μl sterile water.
Formulation Lyophilized. Contains PBS.
Protein Negative Control

Fc (human) IgG1 Control (rec.)

Other Product Data

UniProt link Q9Y6Q6: RANK (human) (precursor)

Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Centrifuge lyophilized vial before opening and reconstitution.
PBS containing at least 0.1% BSA should be used for further dilutions.
Use/Stability Stable for at least 6 months after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

RANK (TRANCE-R; CD265) is the receptor for RANKL/TRANCE/OPGL. It is essential for RANKL-mediated osteoclastogenesis and is involved in the regulation of interactions between T cells and dendritic cells.

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