AdipoGen Life Sciences

DNER (extracellular domain) (human):Fc (human) (rec.)

CHF 170.00
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AG-40A-0119T-C01010 µgCHF 170.00
AG-40A-0119T-C05050 µgCHF 470.00
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Product Details
Synonyms BET; UNQ262/PRO299; Delta and Notch-like Epidermal Growth Factor-related Receptor
Product Type Protein
Properties
Source/Host HEK 293 cells
Sequence

The extracellular domain of human DNER (aa 29-637) is fused at the C-terminus to the Fc portion of human IgG1.

Crossreactivity Human
MW ~120kDa (SDS-PAGE)
Purity ≥90% (SDS-PAGE)
Endotoxin Content <0.06EU/μg purified protein (LAL test; Lonza).
Concentration After reconstitution:
for 10µg size: 0.1mg/ml
for 50µg size: 1 mg/ml
Reconstitution 10µg size: Reconstitute with 100µl sterile water.
50µg size: Reconstitute with 50µl sterile water.
Accession Number NP_620711.3
Formulation Lyophilized from 0.2μm-filtered solution in PBS.
Protein Negative Control

Fc (human) IgG1 Control (rec.)

Other Product Data

UniProt link NP_620711.3: DNER (human)

Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Centrifuge lyophilized vial before opening and reconstitution.
PBS containing at least 0.1% BSA should be used for further dilutions.
Use/Stability Stable for at least 6 months after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

DNER is an activator of the Notch1 pathway. It mediates neuron-glia interaction during astrocytogenesis.

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