AdipoGen Life Sciences

RBP4 (rat) (rec.)

CHF 180.00
In stock
AG-40A-0049-C01010 µgCHF 180.00
AG-40A-0049-C05050 µgCHF 370.00
More Information
Product Details
Synonyms Retinol Binding Protein 4
Product Type Protein
Properties
Source/Host HEK 293 cells
Sequence

Rat RBP4 (aa 19-201) is fused at the N-terminus to a FLAG®-tag.

Crossreactivity Rat
MW ~23kDa (SDS-PAGE)
Purity ≥90% (SDS-PAGE)
Endotoxin Content <0.1EU/μg purified protein (LAL test; Lonza).
Concentration Lot dependent.
Formulation Liquid. 0.2μm-filtered solution in PBS, pH 7.2.
Other Product Data

UniProt link P04916: RBP4 (rat) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After opening, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
For maximum product recovery after thawing, centrifuge the vial before opening the cap.
Use/Stability Stable for at least 6 months after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

Retinol binding protein 4 (RBP4; RBP) is a 21kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.

Product References
  1. Retinol-binding protein 4 and peroxisome proliferator-activated receptor-γ in steatotic liver transplantation: A. Casillas-Ramirez, et al.; J. Pharmacol. Exp. Ther. 338, 143 (2011)
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