AdipoGen Life Sciences

anti-ANGPTL6 (human), pAb

CHF 390.00
In stock
AG-25A-0030-C100100 µgCHF 390.00
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Product Details
Synonyms Angiopoietin-like Protein 6; AGF; Angiopoietin-related Growth Factor
Product Type Polyclonal Antibody
Properties
Source/Host Rabbit
Immunogen/Antigen Synthetic peptide corresponding to aa 114-130 (L114QHEAGPGAGPGADLGA130) of human ANGPTL6.
Application

ELISA: (direct and indirect: 1:2’000-1:5’000)
Western Blot: (1:2’000-1:5’000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.

Crossreactivity Human
Specificity

Recognizes human ANGPTL6. Detects a band of ~52kDa by Western blot.

Purity Detail Protein A-affinity purified.
Concentration 1mg/ml
Formulation Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Isotype Negative Control

Rabbit IgG

Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After opening, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Use/Stability Stable for at least 6 months after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

ANGPTL6 regulates angiogenesis and also directly regulates lipid, glucose, and energy metabolism. The serum levels of ANGPTL6 are significantly increased in obese humans, patients with type 2 diabetes mellitus (T2DM), and in metabolic syndrome.

Product References
  1. Rare Coding Variants in ANGPTL6 Are Associated with Familial Forms of Intracranial Aneurysm: R. Bourcier, et al.; Am. J. Hum. Genet. 102, 133 (2018)
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