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AdipoGen Life Sciences
anti-BAFF-R (human), mAb (HuBR9.1) (Biotin)
450
CHF
CHF 450.00
In stock
AG-20B-0016B-C100100 µgCHF 450.00
Figure 1: Detection of endogenous human BAFF-R with anti-BAFF-R (human), mAb (HuBR9.1) (AG-20B-0016).
BJAB and Jurkat cells were stained with A) 20 μg /ml (and 2-fold dilutions) and B) 2μg /ml of anti-BAFF-R (human), mAb (HuBR9.1) in 50 μl FACS buffer (PBS, 5% fetal calf serum, 0.02% azide), revealed with anti-mouse-PE (1/200) and then analyzed by flow cytometry.
BJAB and Jurkat cells were stained with A) 20 μg /ml (and 2-fold dilutions) and B) 2μg /ml of anti-BAFF-R (human), mAb (HuBR9.1) in 50 μl FACS buffer (PBS, 5% fetal calf serum, 0.02% azide), revealed with anti-mouse-PE (1/200) and then analyzed by flow cytometry.
| Product Details | |
|---|---|
| Synonyms | BAFF Receptor; BR3; BlySR3; CD268; TNFRSF13C |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | HuBR9.1 |
| Isotype | Mouse IgG1 |
| Source/Host | Purified from concentrated hybridoma tissue culture supernatant. |
| Immunogen/Antigen | Cells transfected with human BAFF-R. |
| Label/Conjugates | Biotin |
| Application |
Flow Cytometry |
| Crossreactivity | Human |
| Specificity |
Recognizes human BAFF-R. |
| Purity | ≥95% (SDS-PAGE) |
| Purity Detail | Protein G-affinity purified. |
| Concentration | 0.5mg/ml |
| Formulation | Liquid. In PBS containing 0.02% sodium azide. |
| Isotype Negative Control | |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF-R signaling is essential for B cell development, survival and humoral immune responses.
Product References
- BAFF-R expression correlates with positive selection of immature B cells: R. Tussiwand, et al.; Eur. J. Immunol. 42, 206 (2012)
- A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors: M. Vigolo, et al.; Nat. Commun. 9, 1199 (2018)
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