AdipoGen Life Sciences

anti-FTO (mouse), mAb (FT62-6)

CHF 300.00
In stock
AG-20A-0083-C05050 µgCHF 300.00
AG-20A-0083-C100100 µgCHF 390.00
More Information
Product Details
Synonyms Fat Mass and Obesity-associated Protein; FATSO
Product Type Monoclonal Antibody
Properties
Clone FT62-6
Isotype Mouse IgG1κ
Immunogen/Antigen Recombinant human FTO.
Application

ELISA: (direct and indirect: 1:2’000-1:5’000)
Immunohistochemistry: (paraffin sections (1:100-1:500))
Immunoprecipitation: (5μg/ml per sample in a final reaction volume of 500-1000μl).
Western Blot: (1:2’000-1:5’000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions must be determined individually for each application.

Crossreactivity Mouse
Specificity

Recognizes mouse FTO. Weakly cross-reacts with human FTO. Does not cross-react with rat FTO.

Purity Detail Protein G-affinity purified.
Concentration 1mg/ml
Formulation Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Isotype Negative Control

Mouse IgG1 Isotype Control

Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After opening, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

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