AdipoGen Life Sciences

anti-ANGPTL7 (human), mAb (Kairos 108-4)

CHF 320.00
In stock
AG-20A-0053-C100100 µgCHF 320.00
More Information
Product Details
Synonyms Angiopoietin-like Protein 7; Cornea-derived Transcript 6 Protein
Product Type Monoclonal Antibody
Properties
Clone Kairos 108-4
Isotype Mouse IgG1κ
Immunogen/Antigen Recombinant human full length ANGPTL7.
Application

ELISA: (direct or indirect: 1:2'000-1:5'000)
Immunohistochemistry: (paraffin sections (1:100))
Western blot: (1:2'000-1:5'000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Optimal conditions should be determined individually for each application.

Note: Tested on recombinant proteins and/or target-protein transfected cell lines in ELISA, Western Blot and/or FACS.

Crossreactivity Human
Specificity

Recognizes human ANGPTL7. Detects a band of ~45kDa by Western blot. Weakly cross-reacts with human ANGPTL7-CCD.

Purity Detail Protein G-affinity purified.
Concentration 1mg/ml
Formulation Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Isotype Negative Control

Mouse IgG1 Isotype Control

Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After opening, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

ANGPTL7 is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target gene of the WNT/ beta-catenin signaling pathway, and is a pharmacogenomics target in the fields of oncology and regenerative medicine. Overexpression of ANGPTL7 increases collagen expression and might exert a pathogenic role in glaucoma.

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