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AdipoGen Life Sciences
anti-GITR (mouse), mAb (MGIT 02)
190
CHF
CHF 190.00
In stock
AG-20A-0007-C100100 µgCHF 190.00
Figure 1: FACS: GITR-transfected HEK 293 cells stained significantly using anti-GITR (mouse), mAb (MGIT 02) (Prod. No. AG-20A-0007).
| Product Details | |
|---|---|
| Synonyms | Tumor Necrosis Factor Receptor Superfamily Member 18; Activation-inducible TNFR Family Receptor; Glucocorticoid-induced TNFR-related Protein; CD357; TNFRSF18; AITR |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | MGIT 02 |
| Isotype | Rat IgG2aκ |
| Immunogen/Antigen | Recombinant mouse GITR. |
| Application |
ELISA: (direct and indirect: 1:5'000-1:10'000) Note: Tested on recombinant proteins and/or target-protein transfected cell lines in ELISA, Western Blot and/or FACS. |
| Crossreactivity | Mouse |
| Specificity |
Recognizes mouse GITR. Does not cross-react with human GITR. |
| Purity Detail | Protein G-affinity purified. |
| Concentration | 1mg/ml |
| Formulation | Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. |
| Isotype Negative Control | |
| RRID | AB_2490089 |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
GITR is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediates NF-κB activation via the TRAF2/NIK pathway.
Product References
- Soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) stimulates osteoclast differentiation in response to receptor activator of NF-kappaB ligand (RANKL) in osteoclast cells: H.H. Shin, et al.; Bone 36, 832 (2005)
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