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Wallcharts

     
     
Pattern Recognition Receptors Signaling Wallchart

The innate immune system plays an essential role in the host’s first line of defense against microbial invasion and involves the recognition of PAMPs or DAMPs by pattern recognition receptors (PRRs). Activation of PRRs triggers cell signaling leading to the production of proinflammatory cytokines, chemokines and type 1 interferons, the induction of antimicrobial and inflammatory responses, pyroptotic cell death and the recruitment of phagocytic cells. AdipoGen is a leader in innate immunity research.
 
For an up-to-date overview on AdipoGen's Innate Immunity Reagents please search this website.
 

Released - November 2013
  Pattern Recognition Receptors Signaling Wallchart 2013

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TNF Superfamily Ligands & Receptors Wallchart

Overview on all TNF Superfamily Ligands & Receptors, including a species cross-rectivity table. TNF Superfamily molecules are expressed in cells of the immune system, and they have been linked to an array of pathophysiologies, including cancer, neurologic diseases, cardiovascular diseases, pulmonary diseases, autoimmune diseases and metabolic diseases. AdipoGen is a TNF Superfamily expert, with 15 years of experience in manufacturing TNF superfamily reagents.

For an up-to-date overview on AdipoGen's TNF Superfamily Reagents please search this website.

Released - July 2013
  TNF Superfamily Ligands and Receptors Wallchart 2013

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Cancer & Stem Cell Signaling Wallchart

Overview on different signaling pathway related to Cancer and Stem Cell research. AdipoGen offers a comprehensive panel of specialized Stem Cell Biology products

For an up-to-date overview on AdipoGen's stem cell reagents please search this website.

Released - April 2013
  Cancer & Stem Cell Signaling Wallchart 2013

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Targeting Immune Checkpoint Wallchart

Tumors co-opt certain immune-checkpoint pathways as a major mechanism of immune resistance, particularly against T cells that are specific for tumor antigens. Many of the immune checkpoints are initiated by ligand–receptor interactions, and can be blocked by antibodies or modulated by recombinant forms of ligands or receptors. AdipoGen offers together with Chimerigen and Ancell a broad panel of biologically active immune chekpoint proteins (CTLA-4, PD-1,PDL-L1, LAG-3) and functional active antibodies.

For an up-to-date overview on AdipoGen's Immune Checkpoint reagents please search this website.

Released - April 2013

  Targeting Immune Checkpoint Wallchart 2013

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Inflammasome Wallchart

The inflammasomes activate mainly caspase-1, leading to the processing and secretion of the pro-inflammatory cytokines IL-1beta and IL-18. Assembly of inflammasomes depends on the NOD-like receptor family members, such as the NLRP/NALP proteins. Inflammasomes link pathogenic triggers and metabolic or genotoxic stress signals to the proteolytic processing of interleukins, which promote the inflammatory response. 

For an up-to-date overview on AdipoGen's Inflammasomes reagents please search this website.

Released - March 2012

  Inflammasome Wallchart 2012

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