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Dityrosine [DT] ELISA Kit

JAI-KDT-010E 1 Kit INQ
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Additional Information

Properties
Application Quantitative ELISA
Specificity Specific to dityrosine (tyrosine dimer).
Crossreactivity All
Quantity 96 wells
Range 0.05 - 12 µmol/L
Sample Type Urine
Assay Type Competitive
Detection Type Colorimetric
Origin Manufactured by JaICA.
Product Type Kit
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Do not freeze.
Use/Stability 12 months after the day of manufacturing. See expiry date on ELISA Kit box.
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Manual Download Document Download

Product Description

Tyrosine is one of the major targets of protein oxidation. Dityrosine (DT) is known to be formed when tyrosine is damaged by free radicals, such as reactive oxygen species (ROS), metal-catalyzed oxidation, ultraviolet irradiation, and peroxidases. Dityrosine has been found in atherosclerotic lesions, and lipofuscin of pyramidal neurons of aged human brains. Dityrosine is a specific biomarker for protein oxidation. Dityrosine is reported to exist in various tissues and was also recently detected in urine samples. It is expected to be a novel protein oxdation marker, which is non-invasively detectable. Thie JaICA Dityrosine ELISA kit is designed for quantitative measurement of dityrosine especially in urine samples.

Product References

  1. Immunochemical detection of protein dityrosine in atherosclerotic lesion of apo-E-deficient mice using a novel monoclonal antibody: Y. Kato, et al.; BBRC 275, 11 (2000)
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