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Phomoxanthone A

BVT-0453-M005 5 mg €280.00
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Additional Information

Properties
Formula C38H38O16
MW 750.7
CAS 359844-69-2
Source/Host Chemicals Isolated from fungus Phomopsis sp M4.
Purity >97% (1H-NMR, HPLC)
Appearance Pale yellow solid.
Solubility Soluble in DMSO, methanol or acetone.
Identity Determined by 1H-NMR and MS.
Origin Manufactured by BioViotica.
InChi Key OHHXJWHRQGZQJM-CMDKCIDSSA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Protect from light when in solution.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
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Product Description

  • Mycotoxin
  • Antibacterial against Gram-positive bacteria.
  • Shows antimalarial and antitubercular activity.
  • Anticancer compound. Cytotoxic against several cancer cell lines (pro-apoptotic activity).
  • Active against plant pathogene fungi (e.g. P. oryza, Phyt. infestans).
  • Activator of murine T lymphocytes, NK cells and macrophages.

Product References

  1. Phomoxanthones A and B, novel xanthone dimers from the endophytic fungus Phomopsis species: M. Isaka, et al.; J. Nat. Prod. 64, 1015 (2001)
  2. X-ray Structure Determination, Absolute Configuration and Biological Activity of Phomoxanthone A: B. Elsasser, et al.; Eur. J. Org. Chem. 2005, 4563 (2005)
  3. Anticancer compounds derived from fungal endophytes: their importance and future challenges: R.N. Kharwar, et al.; Nat. Prod. Rep. 28, 1208 (2011)
  4. Isolation of a phomoxanthone A derivative, a new metabolite of tetrahydroxanthone, from a Phomopsis sp. isolated from the mangrove, Rhizhhopora mucronata: Y. Shiono, et al.; Nat. Prod. Commun. 8, 1735 (2013)
  5. Pro-apoptotic and immunostimulatory tetrahydroxanthone dimers from the endophytic fungus Phomopsis longicolla: D. Rönsberg, et al.; J. Org. Chem. 78, 12409 (2013)
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