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Sceliphrolactam

BVT-0418-M001 1 mg $95.00
BVT-0418-M005 5 mg $380.00
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Additional Information

Product Data
Synonyms Sabaramycin A
Properties
Formula C28H35NO6
MW 481.6
CAS 1267888-95-8
Source/Host Chemicals Isolated from Streptomyces echinatus.
Purity ≥93% (HPLC; NMR)
Appearance Yellow powder.
Solubility Soluble in DMSO or pyridine. Slightly soluble in methanol or acetone.
Identity Determined by 1H-NMR.
Origin Manufactured by BioViotica.
Other Product Data NOTE: This compound is very light sensitive, in solid format but especially also in solution. Protect the compound from acids and bases.
InChi Key HRAPIHJIKATMEB-GWVUBWKVSA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light. Protect from light when in solution.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Documents
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Product Description

  • Unusual polyene antibiotic.
  • Antifungal and antibacterial agent.
  • Inhibits amphothericin B-resistant Candida albicans (MIC 4µg/ml).

Product References

  1. Strukturaufklärung von Sabaramycin A und B: K. Baradaran-Heravi; Diss. Univ. Göttingen (Thesis) (1989)
  2. Sceliphrolactam, a polyene macrocyclic lactam from a wasp-associated Streptomyces sp.: D.-C. Oh, et al.; Org. Lett. 13, 752 (2011)
  3. Chemical analyses of wasp-associated Streptomyces bacteria reveal a prolific potential for natural products discovery: M. Poulsen, et al.; PLoS ONE 6, e16763 (2011)
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