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Acetomycin

BVT-0150-M001 1 mg $95.00
BVT-0150-M005 5 mg $285.00
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Product Data
Synonyms NSC350598; 3-Acetyl-5-(acetyloxy)dihydro-3,4-dimethyl-2(3H)furanone; (2R,3S,4S)-4-Acetyl-3,4-dimethyl-5-oxotetrahydro-furan-2-yl acetate
Properties
Formula C10H14O5
MW 214.2
CAS 510-18-9
Source/Host Chemicals Isolated from Streptomyces ramulosus.
Purity ≥98% (HPLC)
Appearance White to off-white crystalline solid.
Solubility Soluble in DMSO or methanol.
Identity Determined by 1H-NMR.
Origin Manufactured by BioViotica.
InChi Key OYMZTORLGBISLR-RHFNHBFPSA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Documents
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Product Description

  • Antibiotic.
  • Antibacterial, antifungal and antiprotozoal.
  • Cytotoxic against several tumor cell lines in vitro.

Product References

  1. The structure of acetomycin. Spectroscopic characterization and X-ray analysis of a bromo derivative: H. Uhr, et al.; J. Antibiot. 38, 1684 (1985)
  2. Biological effects of acetomycin. I. Activity against tumor cells in vitro and in vivo: S.W. Mamber, et al.; J. Antibiot. 40, 73 (1987)
  3. Biological effects of acetomycin. II. Inactivation by esterases in vitro: S.W. Mamber, et al.; J. Antibiot. 40, 77 (1987)
  4. The structure and absolute configuration of acetomycin: F.H. Cano, et al.; Acta Cryst. C. 44, 919 (1988).
  5. Synthesis and in vitro cytotoxicity of acetomycin and related analogs: D. Chen, et al.; Bioorg. Med. Chem. Lett. 5, 759 (1995)
  6. Total synthesis of (±)-acetomycin and design of esterase-resistant analogs: J. Uenishi, et al.; Chem. Pharm. Bull. 47, 517 (1999)
  7. Formation of chiral quaternary carbon stereocenters using silylene transfer reactions: Enantioselective synthesis of (+)-5-epi-acetomycin: S.A. Calad, et al.; Org. Lett. 9, 1037 (2007)
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