Additional Information
| Product Data | |
|---|---|
| Synonyms | Angiotensin-converting Enzyme 2; SARS Receptor |
| Properties | |
| Application | Quantitative ELISA |
| Specificity | Detects human ACE2. Does not cross-react with mouse ACE2 or human ACE. |
| Crossreactivity | Human |
| Quantity | 1 x 96 wells 2 x 96 wells (Twin Plex) |
| Sensitivity | 293pg/ml |
| Range | 0.391 to 25ng/ml |
| Sample Type | Cell Lysate |
| Assay Type | Sandwich |
| Detection Type | Colorimetric |
| Product Type | Kit |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | After standard reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Plate and reagents should reach room temperature before use. |
| Documents | |
| Manual |
Download
|
| Manual TwinPlex |
Download
|
| MSDS |
Download
|
Product Description
The renin-angiotensin system (RAS) regulates system blood pressure and renal function. Angiotensin-converting enzyme 2 (ACE2) is an enzymatically active homolog of ACE, being highly specific for angiotensin cleavage. It has been shown that ACE2 is implicated in pathophysiological states, including myocardial ischaemia, heart failure, renal failure, atherosclerosis, and diabetes. If ACE2 is contributing to the development of hypertension is currently under investigation.
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