ACE2 (human) ELISA Kit

  • AG-45A-0022EK-KI0196 wells INQ
  • AG-45A-0022PP-KI015 x 96 wells INQ
  • AG-45A-0022TP-KI012 x 96 wells INQ
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Additional Information

Product Data
Synonyms Angiotensin-converting Enzyme 2; SARS Receptor
Properties
Application Quantitative ELISA
Specificity Detects human ACE2. Does not cross-react with mouse ACE2 or human ACE.
Crossreactivity Human
Quantity 1 x 96 wells
2 x 96 wells (Twin Plex)
5 x 96 wells (Penta Plex)
Sensitivity 293pg/ml
Range 0.39 to 25ng/ml
Sample Type Cell Culture Supernatant, Urine
Assay Type Sandwich
Detection Type Colorimetric
Product Type Kit
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice After standard reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Plate and reagents should reach room temperature before use.
Documents
Manual Download Document Download
Manual TwinPlex Download Document Download
Manual PentaPlex Download Document Download
MSDS Download Document Download

Product Description

The renin-angiotensin system (RAS) regulates system blood pressure and renal function. Angiotensin-converting enzyme 2 (ACE2) is an enzymatically active homolog of ACE, being highly specific for angiotensin cleavage. It has been shown that ACE2 is implicated in pathophysiological states, including myocardial ischaemia, heart failure, renal failure, atherosclerosis, and diabetes. If ACE2 is contributing to the development of hypertension is currently under investigation.

Product References

  1. Angiotensin-converting enzyme (ACE) and ACE2 levels in the cerebrospinal fluid of patients with multiple sclerosis: M. Kawajiri, et al.; Mult. Scler. 15, 262 (2009)
  2. CSF angiotensin II and angiotensin-converting enzyme levels in anti-aquaporin-4 autoimmunity: T. Matsushita, et al.; J. Neurol. Sci. 295, 41 (2010)
  3. Urinary ACE2 in patients with CKD: S. Mizuiri, et al.; Nephrology (Carlton) 16, 567 (2011)
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