AdipoGen Life Sciences

Adiponectin (rat) ELISA Kit

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AG-45A-0005YTP-KI012 x 96 wellsINQ
AG-45A-0005YEK-KI0196 wellsINQ
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Product Details
Synonyms ACRP30; AdipoQ; apM1; GBP28; Adipocyte complement related protein of 30kDa
Product Type Kit
Properties
Application Set Quantitative ELISA
Specificity

Detects rat adiponectin. Does not cross-react with mouse adiponectin, human adiponectin, rat resistin, rat RELM-α or rat leptin.

Crossreactivity Rat
Quantity

1 x 96 wells
2 x 96 wells (Twin Plex)

Sensitivity 50pg/ml
Range 0.375 to 24ng/ml
Sample Type Cell Culture Supernatant
Plasma
Serum
Assay Type Sandwich
Detection Type Colorimetric
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice After standard reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Plate and reagents should reach room temperature before use.
Use/Stability 12 months after the day of manufacturing. See expiry date on ELISA Kit box.
Documents
Manual Download PDF
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

Adiponectin [ACRP30; AdipoQ] is a promising biomarker of insulin resistance and type 2 diabetes mellitus (T2DM) but also as a potential target for management of the metabolic syndrome. It is a very robust marker that is not prone to degradation or acute inflammatory challenges, is present in relatively high concentrations in the peripheral circulation, and can be collected by a variety of methods. The benefits of using adiponectin assays in clinical settings include, (a) prediction of risk of diabetes and metabolic status and (b) providing a tool to monitor metabolic improvements. Adiponectin exerts anti-atherogenic and anti-inflammatory properties and may be important as a biomarker for obesity-related cardiovascular disease (CVD). New findings showed urinary adiponectin excretion as an independent new biomarker of microvascular and macrovascular damage in T2DM and suggested it as a very promising tool for early cardiovascular disease risk assessment. Adiponectin serum level was also described as a good biomarker of colorectal adenoma, this being related to the positive correlation between obesity and increased risk of cancer at various sites (colorectal, breast, prostate and endometrium).

Product References
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