Additional Information
| Product Data | |
|---|---|
| Synonyms | SARS Receptor; Angiotensin-converting Enzyme 2; ACEH |
| Properties | |
| Source/Host | HEK 293 cells |
| Sequence | Signal peptide sequence and the extracellular domain of mouse ACE2 (aa 1-740) are fused at the C-terminus to a FLAG®-tag. |
| Crossreactivity | Mouse |
| Biological Activity | Converts angiotensin I to angiotensin-(1-9). |
| MW | ~90kDa (SDS-PAGE) |
| Purity | ≥90% (SDS-PAGE) |
| Endotoxin Content | <0.1EU/μg purified protein (LAL test; Lonza). |
| Concentration | 1 mg/ml |
| Formulation | Liquid. 0.2μm-filtered solution in PBS. |
| Other Product Data | UniProt link Q8R0I0: ACE2 (mouse) FLAG is a registered trademark of Sigma-Aldrich Co. |
| Product Type | Protein |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
| Use/Stability | Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS |
Download
|
Product Description
ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional receptor for SARS coronavirus.
No reviews for this product yet.