AdipoGen Life Sciences

FTO (mouse) (rec.) (His)

CHF 265.00
In stock
AG-40A-0127-C01010 µgCHF 265.00
More Information
Product Details
Synonyms Fat Mass and Obesity-associated Protein; FATSO
Product Type Protein
Properties
Source/Host E. coli
Sequence Mouse FTO (aa 2-502) is fused at the N-terminus to a His-tag.
Crossreactivity Mouse
MW ~55kDa (SDS-PAGE)
Purity ≥90% (SDS-PAGE)
Purity Detail Purified using Ni-NTA column and FPLC.
Endotoxin Content <1EU/μg purified protein (LAL test; Lonza).
Concentration ~0.5mg/ml
Formulation Liquid. 0.2μm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl.
Other Product Data UniProt link Q8BGW1: FTO (mouse)
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After opening, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
For maximum product recovery after thawing, centrifuge the vial before opening the cap.
Use/Stability Stable for at least 6 months after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

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