Additional Information
| Product Data | |
|---|---|
| Synonyms | OB Gene Product; Obese Factor |
| Properties | |
| Clone | HLEP 155 |
| Isotype | Mouse IgG1κ |
| Immunogen/Antigen | Recombinant human leptin. |
| Application | ELISA: (direct or indirect: 1:5'000-1:10'000) Western blot: (1:2'000-1:10'000 using ECL). Optimal conditions should be determined individually for each application. |
| Crossreactivity | Human |
| Specificity | Recognizes human leptin. Detects a band of ~16kDa by Western blot. Does not cross-react with mouse or rat leptin. |
| Purity Detail | Protein G-affinity purified. |
| Concentration | 1mg/ml |
| Formulation | Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. |
| Product Type | Monoclonal Antibody |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | After receipt, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
| Documents | |
| MSDS | 
Download |
Product Description
Leptin is involved in the signaling pathway that regulates the size of the body fat depot. An increase in the level of leptin may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. Defects in the leptin gene may be a cause of autosomal recessive obesity.
Western Blot analysis using anti-Leptin (human), mAb (HLEP 155) (Prod. No. AG-20A-0019) at 1:5000 dilution.
1: Recombinant human Leptin protein.
2: Human Leptin Fc-fusion protein.
1: Recombinant human Leptin protein.
2: Human Leptin Fc-fusion protein.
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